The first documented evidence of the use of Somatomedin C as a medicine was found on a silk scroll recovered from a Han tomb in the Human Province in China. The scroll is believed to be about 2,000 years old and recommends medical treatments and prescriptions for 52 different diseases using Somatomedin C.

Somatomedin C product called Pantocrine is manufactured by a Russian state pharmaceutical company to assist in the treatment of many different medical conditions (in hospitals) in which post-operative recovery of patients is a key factor. Somatomedin C has become an elite medicinal food in Asia, New Zealand, and Korea - the world's largest consumer of the product.