| Short description |
|
Melatonin
is a hormone that is produced by the pineal gland deep within the centre
of the brain. Its production is controlled by light passing through to
the retina and relaying a message to the hypothalamus in the middle brain.
As soon as the ambient light intensity drops below a certain level, the
melatonin production in the pineal gland commences. The hypothalamus serves
as a sort of internal clock in this cycle. Each day, the light entering
our eyes sets the timing mechanism (zeitgeber). Each night, the hypothalamus
- or rather the so-called suprachiasmatic nuclei (SCN) - send a signal
along a pathway into the pineal gland and on this basis this "intelligent
gland" determines the amount of melatonin to be produced. Because
melatonin is produced during periods of darkness, the duration of daylight
affects its ebb and flow. This in turn can affect the sleeping/waking
cycles, generally known as circadian rhythms. By the age of 45 the normal
function of the pineal gland starts to falter, causing melatonin production
to drop to about half. As age increases, melatonin production declines
dramatically. Between the ages of seventy and eighty the amount of melatonin
in the bloodstream becomes almost undetectable.
|